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Acta Academiae Medicinae Sinicae ; (6): 293-297, 2012.
Article in English | WPRIM | ID: wpr-352912

ABSTRACT

Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.


Subject(s)
Humans , Colorectal Neoplasms, Hereditary Nonpolyposis , Diagnosis , Genetics , Pathology , DNA Mismatch Repair , Microsatellite Instability
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